Manon Heyne studied singing at the Royal Conservatory in The Hague herself and graduated in 1991. She received the highest diploma with special distinction. She participated in several productions of the Dutch National Opera (like Die Glückliche Hand by Schoenberg, Life with an Idiot by Schnittke and Broken Strings by Param Vir).
She performs regularly with the Netherlands Chamber Choir in projects with both early, classical and contemporary music. As a soloist she has her own ensemble, specializing in the twentieth century repertoire.
Since 1994 she is teaching at the Royal Conservatoire.